What conditions cause factor inhibitors to occur?

Updated: Feb 07, 2020
  • Author: Bishnu Prasad Devkota, MD, MHI, FRCS(Edin), FRCS(Glasg), FACP; Chief Editor: Eric B Staros, MD  more...
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They are present in factor VIII inhibitors, which are IgG antibodies against factor VIII, occur in hemophilia A (alloantibodies). As autoantibodies they usually arise spontaneously, particularly in the elderly population, but they are also found in pregnancy and autoimmune disease.

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