What is the reference range for factor IX?

Updated: Feb 04, 2020
  • Author: Bishnu Prasad Devkota, MD, MHI, FRCS(Edin), FRCS(Glasg), FACP; Chief Editor: Eric B Staros, MD  more...
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Answer

Answer

Factor IX (plasma thromboplastin component [PTC]) is produced in the liver. It is a single-chain zymogen with a molecular weight of 57 kd and a plasma half-life of 18-24 hours. It binds effectively to collagen not only in vitro [1] but also, apparently, in vivo, and this may account for the finding that when factor IX is infused into hemophilia B patients, recovery is only 50% of what was expected.

The reference range for factor IX is between 60% and 140% of normal values. [2]


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