What causes a decrease in factor VII?

Updated: Feb 05, 2020
  • Author: Bishnu Prasad Devkota, MD, MHI, FRCS(Edin), FRCS(Glasg), FACP; Chief Editor: Eric B Staros, MD  more...
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A congenital deficiency of factor VII has been linked to the following :

  • Variable hemorrhagic diathesis in homozygotes

Acquired conditions leading to its deficiency include the following:

  • Liver disease

  • Vitamin K deficiency

  • Treatment with vitamin K antagonists

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