What causes a decrease in factor V?

Updated: Feb 05, 2020
  • Author: Bishnu Prasad Devkota, MD, MHI, FRCS(Edin), FRCS(Glasg), FACP; Chief Editor: Eric B Staros, MD  more...
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Factor V is decreased in the following congenital conditions:

  • Inherited autosomal deficiency

  • Bleeding in homozygotes

Factor V is also decreased in the following acquired conditions:

  • Liver disease

  • Pathologic fibrinolysis

  • Disseminated intravascular coagulation (DIC)

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