How is a diagnosis of pleural desmoplastic small round cell tumor (DSRCT) confirmed?

Updated: Dec 25, 2019
  • Author: Joseph F Tomashefski, Jr, MD; more...
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Answer

Answer

When in doubt regarding the differential diagnosis or for DSRCTs with atypical histological or immunohistochemical features, demonstration of the characteristic cytogenetic translocation or gene fusion product EWS-WT1 supports the diagnosis of DSRCT.


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