Which conditions are included in the differential diagnoses of pleural synovial sarcoma?

Updated: Dec 25, 2019
  • Author: Joseph F Tomashefski, Jr, MD; more...
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Answer

Major differential diagnostic considerations of biphasic pleural synovial sarcoma include biphasic mesothelioma, pulmonary carcinosarcoma secondarily involving the pleura, and pleuropulmonary blastoma. [94] Mesothelioma occurs in an older population and is usually diffuse or multifocal within the pleura compared to the localized mass of synovial sarcoma. The spindle cell component of synovial sarcoma is less pleomorphic and more densely compact than mesothelioma.


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