What is the role of genetic studies in the diagnosis of pleural desmoplastic small round cell tumor (DSRCT)?

Updated: Dec 25, 2019
  • Author: Joseph F Tomashefski, Jr, MD; more...
  • Print
Answer

Answer

DSRCT is associated with the translocation t(11;22)(p13;q12), which gives rise to the WT1-EWS gene fusion product. This translocation is considered to be specific for DSRCT, regardless of its site of origin. [67, 76, 83, 84]


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!