What are nonmesothelial cancers of the pleura?

Updated: Dec 25, 2019
  • Author: Joseph F Tomashefski, Jr, MD; more...
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Nonmesotheliomatous cancers of the pleura include an assortment of malignant neoplasms that primarily or secondarily involve pleura. [1, 2] They enter into the clinical and histological differential diagnoses of pleural malignant mesothelioma. Using an approach that includes consideration of the morphologic features, appropriate immunohistochemistry, and correct clinical context aids in making the proper diagnosis. [2]

The distinction among these various tumors is important both clinically and epidemiologically. Whereas pleural mesothelioma is highly associated with asbestos exposure, nonmesotheliomatous cancers have generally not been proven to result from exposure to airborne asbestos. This article discusses the following neoplasms: [3]

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