What is pulmonary alveolar proteinosis (PAP)?

Updated: Dec 18, 2019
  • Author: Rodolfo Laucirica, MD; Chief Editor: Philip T Cagle, MD  more...
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Answer

Answer

Pulmonary alveolar proteinosis (PAP) is a rare disease characterized by the accumulation of granular eosinophilic material within alveolar spaces. [1]  PAP has also been referred to as pulmonary alveolar phospholipoproteinosis or alveolar lipoproteinosis, reflecting the abundance of lipids within the granular exudate. PAP has a worldwide distribution and an estimated incidence of 0.2 case per million population. [1]


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