What is the efficacy of unrelated-donor (URD) transplantation for the treatment of acute lymphoblastic leukemia (ALL)?

Updated: Jul 02, 2021
  • Author: Karen Seiter, MD; Chief Editor: Emmanuel C Besa, MD  more...
  • Print

For patients without a sibling donor, an alternative is an unrelated-donor (URD) transplant. Weisdorf et al found that autologous BMT was associated with a lower transplant-related mortality rate, but URD transplantations had a lower risk of relapse. [72] In patients whose disease was in second CR, URD transplantations resulted in a superior rate of disease-free survival. [72]

Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!