What is the role of the hyper-CVAD regimen in the treatment of acute lymphoblastic leukemia (ALL)?

Updated: Feb 20, 2020
  • Author: Karen Seiter, MD; Chief Editor: Emmanuel C Besa, MD  more...
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An alternative is the hyper-CVAD regimen, which is based on the success achieved with short-term, dose-intensive chemotherapy regimens in children. It incorporates hyperfractionated cyclophosphamide and intensive doses of cytarabine (Ara-C) and methotrexate in combination with dexamethasone and vincristine.

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