Which studies and procedures are performed in the workup of acute lymphoblastic leukemia (ALL)?

Updated: Feb 20, 2020
  • Author: Karen Seiter, MD; Chief Editor: Emmanuel C Besa, MD  more...
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The following studies and procedures are used in the workup for acute lymphoblastic leukemia (ALL):

  • Complete blood count (CBC) with peripheral smear
  • Coagulation studies (prothrombin time [PT], activated partial thromboplastin time [aPTT], fibrinogen)
  • Chemistry profile, including liver and renal function studies
  • Bone marrow aspiration and biopsy – Definitive diagnostic tests
  • Cultures; in particular, blood cultures
  • Chest radiography
  • Chest computed tomography (CT) scan, as indicated by symptoms
  • Multiple-gated acquisition (MUGA) scan or echocardiogram

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