What is the prevalence of acute lymphoblastic leukemia (ALL)?

Updated: Jun 20, 2019
  • Author: Karen Seiter, MD; Chief Editor: Emmanuel C Besa, MD  more...
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Acute lymphoblastic leukemia (ALL) is the most common type of cancer and leukemia in children in the United States. ALL accounts for 74% of pediatric leukemia cases. [11]

In adults, ALL is less common than acute myeloid leukemia (AML). It is estimated that there will be 5930 cases of ALL (adult and pediatric) in the United States in 2019, resulting in 1500 deaths. [12] The estimated 5-year survival is 68.6%. The favorable survival rate is due to the high cure rate of ALL in the pediatric population; patients younger than 20 years account for 54.2% of new cases but only 14.3% of deaths. Prognosis declines with increasing age, and the median age at death is 56 years. Patients 65 to 74 years old account for 6.9% of new cases but 16.4% of deaths. [11]

Worldwide, the highest incidence of ALL occurs in Italy, the United States, Switzerland, and Costa Rica In Europe overall, B-cell precursor ALL has been increasing by around 1% each year. [2]

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