What is the prevalence of acute lymphoblastic leukemia (ALL)?

Updated: Oct 26, 2020
  • Author: Karen Seiter, MD; Chief Editor: Emmanuel C Besa, MD  more...
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Acute lymphoblastic leukemia (ALL) is the most common type of cancer and leukemia in children in the United States. Median age at diagnosis is 16 years. [11] ALL accounts for 74% of pediatric leukemia cases. [12]

In adults, ALL is less common than acute myeloid leukemia (AML). The American Cancer Society estimates that 6150 cases of ALL (adult and pediatric) will occur in the United States in 2020, resulting in 1520 deaths. [12] The estimated 5-year survival is 68.6%. The favorable survival rate is due to the high cure rate of ALL in children. Prognosis declines with increasing age, and the median age at death is 56 years. [11]

Worldwide, the highest incidence of ALL occurs in Italy, the United States, Switzerland, and Costa Rica In Europe overall, B-cell precursor ALL has been increasing by around 1% each year. [2]

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