What are the treatment options for treatment of newly-diagnosed acute lymphoblastic leukemia (ALL)?

Updated: Feb 20, 2020
  • Author: Karen Seiter, MD; Chief Editor: Emmanuel C Besa, MD  more...
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Treatment of newly-diagnosed ALL may include the following:

  • Induction chemotherapy (eg, standard 4- or 5-drug regimen, ALL-2, or hyper-CVAD)
  • Consolidation chemotherapy
  • Maintenance chemotherapy
  • Inclusion of tyrosine kinase inhibitors for Philadelphia chromosome positive patients
  • Inclusion of rituximab for CD20+ patients (especially those <  60 years)
  • Intrathecal chemotherapy for central nervous system (CNS) prophylaxis
  • Stem cell transplantation
  • Supportive care (eg, blood products, antibiotics, growth factors)

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