How is anemia managed in paroxysmal nocturnal hemoglobinuria (PNH)?

Updated: May 20, 2021
  • Author: Emmanuel C Besa, MD; Chief Editor: Sara J Grethlein, MD, FACP  more...
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Answer

Determine steady-state hemoglobin levels after correction for iron deficiency. When appropriate, transfuse packed red blood cells (RBCs) with leukocytes depleted by filter. Washing RBCs is no longer necessary, and use of irradiated blood products is recommended for future stem cell transplantation.


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