How is classic paroxysmal nocturnal hemoglobinuria differentiated from paroxysmal nocturnal hemoglobinuria (PNH) in other bone marrow disorders?

Updated: May 20, 2021
  • Author: Emmanuel C Besa, MD; Chief Editor: Sara J Grethlein, MD, FACP  more...
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Answer

Bone marrow examination will differentiate classic PNH from PNH that develops in the setting of other bone marrow disorders. [24] In addition, bone marrow examination will identify an erythroid and hyperplastic bone marrow during the hemolytic phase or a hypoplastic bone marrow in the aplastic phase.


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