What are the symptoms of deficient hematopoiesis in paroxysmal nocturnal hemoglobinuria (PHN)?

Updated: May 20, 2021
  • Author: Emmanuel C Besa, MD; Chief Editor: Sara J Grethlein, MD, FACP  more...
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Answer

Patients with deficient hematopoiesis usually present with anemia, despite the presence of an erythroid marrow with suboptimal reticulocytosis. In some cases, neutropenia and thrombocytopenia can occur in a hypoplastic bone marrow similar to aplastic anemia (aplastic episodes).


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