What are the frequently reported symptoms of paroxysmal nocturnal hemoglobinuria (PNH)?

Updated: May 20, 2021
  • Author: Emmanuel C Besa, MD; Chief Editor: Sara J Grethlein, MD, FACP  more...
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A study of the first 1610 patients enrolled in the International PNH Registry found that overall, 16% of patients had a history of thrombotic events and 14% a history of impaired renal function. Frequently reported symptoms included the following [16] :

  • Fatigue (80%)
  • Dyspnea (64%)
  • Hemoglobinuria (62%)
  • Abdominal pain (44%)
  • Chest pain (33%)

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