What is the prevalence of paroxysmal nocturnal hemoglobinuria (PNH) in the US?

Updated: May 20, 2021
  • Author: Emmanuel C Besa, MD; Chief Editor: Sara J Grethlein, MD, FACP  more...
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Paroxysmal nocturnal hemoglobinuria (PNH) is an uncommon disorder of unknown frequency both in the United States and worldwide. There is little information on the incidence of PNH, but the rate is estimated to be 5-10 times less than that of aplastic anemia; thus, PNH is a rare disease.

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