What is the role of deferasirox in the treatment of myelodysplastic syndrome (MDS)?

Updated: Jul 24, 2018
  • Author: Emmanuel C Besa, MD; Chief Editor: Koyamangalath Krishnan, MD, FRCP, FACP  more...
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Answer

Deferasirox (Exjade) is an FDA-approved dispersible tablet that is dissolved in 7 oz of water and taken by mouth once daily. It is excreted in stools rather than urine, and it is 100-fold more active as a chelator of iron. Patients who cannot tolerate side effects such as diarrhea may require dose modification.


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