What are the French-American-British (FAB) classifications of myelodysplastic syndrome (MDS)?

Updated: Jul 24, 2018
  • Author: Emmanuel C Besa, MD; Chief Editor: Koyamangalath Krishnan, MD, FRCP, FACP  more...
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Answer

The FAB system classifies MDS into the following five subgroups, differentiating them from acute myeloid leukemia [14] :

  • Refractory anemia (RA)

  • RA with ringed sideroblasts (RARS)

  • RA with excess blasts (RAEB; 6-20% myeloblasts)

  • RAEB in transition to AML (RAEB-T; 21-30% myeloblasts)

  • Chronic myelomonocytic leukemia (CMML)

An underlying trilineage dysplastic change in the bone marrow cells is found in all subtypes.


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