What is the role of imaging studies in the workup of solitary plasmacytoma?

Updated: Mar 10, 2021
  • Author: Suzanne R Fanning, DO; Chief Editor: Emmanuel C Besa, MD  more...
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Answer

Solitary plasmacytoma (SP) shows nonspecific computed tomography (CT) and magnetic resonance imaging (MRI) findings. [40] Fluorodeoxyglucose positron emission tomogrpahy (FDG-PET) is the modality of choice for assessment of the skeletal abnormalities. [40] Whole-body PET/CT or MRI should be performed to exclude the presence of additional malignant lesions; the use of both may provide complementary information. [41] In a series of 43 cases, an abnormal involved serum free light chain (FLC) value and the presence of at least two hypermetabolic lesions on FDG-PET at diagnosis of SP were reported as the two predictors of early evolution. [42]


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