Which clinical history findings are characteristic of solitary bone plasmacytoma (SBP)?

Updated: Dec 31, 2019
  • Author: Suzanne R Fanning, DO; Chief Editor: Emmanuel C Besa, MD  more...
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Answer

The most common symptom of solitary bone plasmacytoma (SBP) is pain at the site of the skeletal lesion due to bone destruction by the infiltrating plasma cell tumor. [7, 17]

Compression fractures of the thoracic and lumbar vertebral bodies usually result in severe spasms and back pain. Patients with significant vertebral involvement may also have evidence of nerve root or spinal cord compression. [7] Spinal cord compression represents an emergency that requires immediate diagnosis and treatment to avoid permanent neurologic damage (eg, paraplegia, bowel and bladder dysfunction, chronic pain).

Pleuritic pain from pathologic rib and clavicular fractures are associated with marked local tenderness.


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