Which medications in the drug class Estrogens are used in the treatment of von Willebrand Disease?

Updated: Dec 30, 2019
  • Author: Eleanor S Pollak, MD; Chief Editor: Srikanth Nagalla, MBBS, MS, FACP  more...
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Answer

Estrogens

Estrogen may be helpful in reducing menorrhagia. Even in type III disease, in which case vWF and FVIII levels are not necessarily increased, estrogen may mediate changes in the endometrium that lessen menstrual bleeding severity.

Ethinyl estradiol and levonorgestrel (Levora, Nordette, Lutera, Trivora)

Ethinyl estradiol reduces the secretion of luteinizing hormone and follicle-stimulating hormone from the pituitary by decreasing the amount of gonadotropin-releasing hormones.


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