How does pregnancy affect the levels of von Willebrand factor (vWF) in patients with non-type 3 von Willebrand disease (vWD)?

Updated: Dec 30, 2019
  • Author: Eleanor S Pollak, MD; Chief Editor: Srikanth Nagalla, MBBS, MS, FACP  more...
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During pregnancy, the vWF level increases in most patients with non–type 3 vWD. Thus, in patients with functionally normal vWF, labor and delivery usually proceed normally.  Measurement of vWF levels is recommended in the third trimester of pregnancy to facilitate peri-partum planning. [27]

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