Which ristocetin cofactor (RCoF) value is diagnostic of von Willebrand disease (vWD)?

Updated: Dec 30, 2019
  • Author: Eleanor S Pollak, MD; Chief Editor: Srikanth Nagalla, MBBS, MS, FACP  more...
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Normal RCoF values are 50-200 IU/dL. A level below 30 IU/dL is considered definitive for vWD, although levels of 30-50 IU/dL may be found in some patients with type 1 or 2 vWD. [13]

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