What is the most common type of von Willebrand disease (vWD)?

Updated: Dec 30, 2019
  • Author: Eleanor S Pollak, MD; Chief Editor: Srikanth Nagalla, MBBS, MS, FACP  more...
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Answer

vWD type 2 is further divided into four variants (2A, 2B, 2N, 2M), based on characteristics of dysfunctional vWF. These categories correspond to distinct molecular mechanisms, with corresponding clinical features and therapeutic recommendations. (See Etiology, Workup, and Treatment.) In a review of 670 French families with von Willebrand Disease, the distribution of VWD types was as follows [1] :

  • Type 1 – 25%
  • Type 2 – 66%
  • Type 3 – 8%
  • Unknown type – 1%

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