Which medications in the drug class Osmotic Diuretics are used in the treatment of Transfusion Reactions?

Updated: Jan 02, 2019
  • Author: S Gerald Sandler, MD, FACP, FCAP; Chief Editor: Emmanuel C Besa, MD  more...
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Answer

Osmotic Diuretics

Osmotic agents increase the osmolarity of the glomerular filtrate and induce diuresis. This, in turn, hinders the tubular reabsorption of water, also causing sodium and chloride excretion to increase.

Mannitol injection 20% USP (Osmitrol)

An obligatory osmotic diuretic only slightly metabolized and excreted by the kidney. Induces diuresis by increasing the osmolarity of the glomerular filtrate, thereby hindering tubular reabsorption of water. Excretion of sodium and chloride is also enhanced.


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