What causes circulatory (volume) overload transfusion reactions?

Updated: Jan 02, 2019
  • Author: S Gerald Sandler, MD, FACP, FCAP; Chief Editor: Emmanuel C Besa, MD  more...
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Answer

Increased fluid volume in susceptible patients, including those with cardiovascular compromise, elderly patients, and small children, may result in pulmonary edema. A usual transfusion rate is 2-2.5 mL/kg per hour. In at-risk patients, blood products can be transfused at a slower rate.


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