Which medications in the drug class Chemotherapy agents are used in the treatment of Thrombotic Thrombocytopenic Purpura (TTP)?

Updated: May 25, 2021
  • Author: Theodore Wun, MD, FACP; Chief Editor: Srikanth Nagalla, MD, MS, FACP  more...
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Chemotherapy agents

These agents are used as an adjunct to plasma exchange.

Vincristine (Oncovin, Vincasar)

Mechanism of action uncertain. May involve a decrease in reticuloendothelial cell function or increase in platelet production. However, neither of these mechanisms fully explains the effect in TTP and HUS.

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