What are the discharge criteria following inpatient treatment of thrombotic thrombocytopenic purpura (TTP)?

Updated: May 25, 2021
  • Author: Theodore Wun, MD, FACP; Chief Editor: Srikanth Nagalla, MD, MS, FACP  more...
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Patients with TTP should remain hospitalized until at least a partial response is achieved. Criteria for discharge include the following:

  • Resolution of altered mental status
  • Improved platelet count
  • Reduced LDH level
  • Stable hemoglobin level

In some patients, intravenous access will become a concern. Large-bore dual-lumen apheresis catheters are now readily available and many are now placed by interventional radiology services. The patient and/or a caregiver can be instructed in the proper care of these catheters.

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