When is a syphilis screening test indicated in the management of HIV infection in primary care?

Updated: Apr 09, 2019
  • Author: Jason F Okulicz, MD, FACP, FIDSA; Chief Editor: Michael Stuart Bronze, MD  more...
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Perform syphilis screening upon entry into care and at least annually in sexually active HIV-infected persons and frequent screening (every 3-6 months) in those considered high risk. A lumbar puncture should always be performed in patients with a reactive syphilis serology who have neurologic or ocular symptoms or signs (irrespective of past syphilis treatment) and in those who experience serologic treatment failure.

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