Does an elevated level of serum phospholipase A2 predict acute chest syndrome (ACS) in patients with sickle cell disease (SCD)?

Updated: May 12, 2021
  • Author: Joseph E Maakaron, MD; Chief Editor: Emmanuel C Besa, MD  more...
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Answer

Elevated levels of serum phospholipase A2 levels have been found to be associated with ACS and might predict its occurrence. In pilot studies, transfusion of patients who had pain, fever, and increased serum phospholipase A2 levels have apparently thwarted development of ACS. [87]


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