What is the suggested schedule for routine lab testing for sickle cell disease (SCD)?

Updated: May 12, 2021
  • Author: Joseph E Maakaron, MD; Chief Editor: Emmanuel C Besa, MD  more...
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Answer

Obtaining a series of baseline values on each patient to compare with those at times of acute illness is useful. The table below shows a typical schedule of routine clinical laboratory evaluations.

Table. Schedule of Laboratory Tests for Patients With Sickle Cell Disease (Open Table in a new window)

Tests

Age

Frequency

CBC count with WBC differential,

reticulocyte count

3-24 mo

>24 mo

every 3 mo

every 6 mo

Percent Hb F

6-24 mo

>24 mo

every 6 mo

annually

Renal function (creatinine, BUN, urinalysis)

≥ 12 mo

annually

Hepatobiliary function (ALT, fractionated bilirubin)

≥ 12 mo

annually

Pulmonary function (transcutaneous O2 saturation)

≥ 12 mo

every 6 mo


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