Which factors often precede aplastic crises in sickle cell disease (SCD)?

Updated: May 12, 2021
  • Author: Joseph E Maakaron, MD; Chief Editor: Emmanuel C Besa, MD  more...
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Aplastic crises are often preceded by the following:

  • Infection with parvovirus B19
  • Folic acid deficiency
  • Ingestion of bone marrow toxins (eg, phenylbutazone)

Acute chest syndrome has been linked to the following:

  • Fat embolism
  • Infections
  • Pain episodes
  • Asthma [15]

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