When is endocarditis prophylaxis indicated for surgical procedures of the skin, skin structure, or musculoskeletal tissue?

Updated: Jun 01, 2020
  • Author: Samah Alasrawi, MD; Chief Editor: Buck Christensen  more...
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Answer

Answer

Patients with high cardiac risk who undergo a surgical procedure that involves infected skin, skin structure, or musculoskeletal tissue should receive an agent active against staphylococci and beta-hemolytic streptococci (eg, antistaphylococcal penicillin, cephalosporin).

If the causative organism of respiratory, skin, skin structure, or musculoskeletal infection is known or suspected to be Staphylococcus aureus, administer an antistaphylococcal penicillin or cephalosporin, or vancomycin (if patient is unable to tolerate beta-lactam antibiotics). Vancomycin is recommended for known or suspected methicillin-resistant strains of S aureus.


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