How is the prognostic score for Waldenstrom macroglobulinemia/lymphoplasmacytic lymphoma determined?

Updated: Jan 04, 2018
  • Author: Joseph M Tuscano, MD; Chief Editor: Emmanuel C Besa, MD  more...
  • Print
Answer

Answer

Each of the following positive prognostic factors is assigned a value of one, with the final sum used to assess prognostic score and predicted survival: [2]

  • IgM level >7 g/dL

  • Age >65 years

  • Hemoglobin level ≤11.5 g/dL

  • Platelet count ≤100,000/µL

  • Beta2-microglobulin level >3 µg/mL

The sum is then used to estimate prognosis and survival (see Table 1).

Table 1. Assessment of Prognostic Score and Predicted Survival (Open Table in a new window)

Score

Stratum

Median Survival (mo)

0-1a

Low

142

2b

Intermediate

96

>2

High

43

a Except age.

b Age >65 years is also intermediate risk.


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!