How is nonbulky symptomatic Waldenstrom macroglobulinemia treated?

Updated: Aug 06, 2020
  • Author: Joseph M Tuscano, MD; Chief Editor: Emmanuel C Besa, MD  more...
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Answer

Answer

Signs and symptoms in patients with non-bulky WM/LPL may be IgM mediated or tumor related. IgM-mediated manifestations include the following [3] :

Consider single-agent rituximab therapy for patients with non-bulky symptomatic WM/LPL:

  • Rituximab 375 mg/m 2 IV once weekly x 4 weeks

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