What are the IV chemotherapy regimens used to treat stage II-IV fallopian tube carcinoma in patients unable to tolerate IP chemotherapy?

Updated: Aug 20, 2019
  • Author: from Memorial Sloan-Kettering - Elizabeth L Jewell, MD, MHSc; Chief Editor: from Memorial Sloan-Kettering - Yukio Sonoda, MD  more...
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Answer

Answer

If the patient is unable to tolerate IP chemotherapy, debulking has been suboptimal (ie, disease >1 cm), disease has spread to the liver parenchyma, or the patient has malignant plural effusions, one of the following IV regimens should be considered:

  • Paclitaxel 135-175 mg/m2 IV infused over 3 h plus  carboplatin AUC 5-7.5 IV infused over 30-60 min every 21 d for six cycles [11] or

  • Docetaxel 60-75 mg/m2 infused over 1 h plus  carboplatin AUC 5-6 IV infused over 1 h every 21 d for three to six cycles [7]


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