What are the IP chemotherapy regimens used to treat stage II-III fallopian tube carcinoma following optimal tumor debulking?

Updated: Aug 20, 2019
  • Author: from Memorial Sloan-Kettering - Elizabeth L Jewell, MD, MHSc; Chief Editor: from Memorial Sloan-Kettering - Yukio Sonoda, MD  more...
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Answer

Answer

Patients who have undergone optimal tumor debulking should be offered IP chemotherapy. The following dosing regimen is recommended:

  • Paclitaxel 135 mg/m2 IV infused over 24 h on day 1 (may be given over 3 h if tolerated) plus cisplatin 100 mg/m2 IP on day 2 (may be reduced to 75 mg/m2 and given on day 1 or  day 2 to allow an outpatient regimen) plus  paclitaxel 60 mg/m2 IP on day 8 every 21 d for six cycles [8, 9, 10]


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