How is carboplatin dosed in the treatment of fallopian tube carcinoma?

Updated: Aug 20, 2019
  • Author: from Memorial Sloan-Kettering - Elizabeth L Jewell, MD, MHSc; Chief Editor: from Memorial Sloan-Kettering - Yukio Sonoda, MD  more...
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Answer

Answer

In the treatment recommendations below, note that carboplatin is dosed to achieve a targeted area under the curve (AUC), which is defined as the area under the concentration-versus-time curve and expressed in mg/mL/min. The calculation is based on the Calvert formula [5] (see the Carboplatin AUC Dose Calculation (Calvert formula) calculator). The maximum dose is based on the maximum estimated glomerular filtration rate (GFR).


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