What are the signs and symptoms of protein S deficiency?

Updated: Jan 03, 2021
  • Author: Mohammad Muhsin Chisti, MD, FACP; Chief Editor: Perumal Thiagarajan, MD  more...
  • Print
Answer

Signs and symptoms of protein S deficiency are those associated with deep venous thrombosis (DVT), thrombophlebitis, or pulmonary embolus. Some women may have fetal loss as their only manifestation of a thrombophilic disorder (eg, protein S deficiency).

With venous thrombosis of the lower limbs, lower limb swelling and discomfort are the usual symptoms. Occasionally, redness or discoloration also is present, with or without associated cellulitis.


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!