Which medications in the drug class Antihistamines, 1st Generation are used in the treatment of Interstitial Cystitis?

Updated: Dec 04, 2020
  • Author: Eric S Rovner, MD; Chief Editor: Edward David Kim, MD, FACS  more...
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Answer

Antihistamines, 1st Generation

Antihistamines inhibit binding to the H1 histamine receptor.

Hydroxyzine (Vistaril)

Hydroxyzine is an H1 histamine receptor blocker that may inhibit mast cell secretion and may suppress histamine activity in the subcortical region of the central nervous system (CNS). Adult dosing is 25-75mg/day orally. Hydroxyzine is a pregnancy category C drug.


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