What are potential mechanisms for the effectiveness of intradetrusor onabotulinumtoxinA (OBA) in the treatment of interstitial cystitis/bladder pain syndrome (IC/BPS)?

Updated: Dec 04, 2020
  • Author: Eric S Rovner, MD; Chief Editor: Edward David Kim, MD, FACS  more...
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Answer

Potential mechanisms for the effectiveness of OBA include down-regulation of vascular endothelial growth factor (VEGF) and an afferent sensory effect. [106]


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