What is the role of intravesical bacillus Calmette-Guérin (BCG) in the treatment of interstitial cystitis/bladder pain syndrome (IC/BPS)?

Updated: Dec 04, 2020
  • Author: Eric S Rovner, MD; Chief Editor: Edward David Kim, MD, FACS  more...
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Answer

Intravesical bacillus Calmette-Guérin (BCG) has been hypothesized to suppress inflammation within the bladder. A randomized, placebo-controlled trial in patients with refractory interstitial cystitis revealed borderline statistical significance for global response assessment questioning, as well as most secondary outcome measures, including capacity, pain scores, urgency/frequency symptoms, and interstitial cystitis inventories. [86] As with resiniferatoxin, the AUA currently recommends against this treatment. [80]


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