What is the role of pentosan polysulfate sodium in the treatment of interstitial cystitis/bladder pain syndrome (IC/BPS)?

Updated: Dec 04, 2020
  • Author: Eric S Rovner, MD; Chief Editor: Edward David Kim, MD, FACS  more...
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Answer

A study funded by the National Institutes of Health found that using pentosan polysulfate sodium alone or in combination with hydroxyzine was slightly beneficial, but this was not significant. The study compared placebo with oral pentosan polysulfate sodium, hydroxyzine, and a combination of both. [66]


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