What are theories for dietary exacerbations in interstitial cystitis/bladder pain syndrome (IC/BPS)?

Updated: Dec 04, 2020
  • Author: Eric S Rovner, MD; Chief Editor: Edward David Kim, MD, FACS  more...
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Answer

Common theories for dietary exacerbations include the hypothesis that the disrupted urothelial barrier is sensitive to metabolites of these foods. Alternative theories include the mechanism of "cross-talk," or the idea that stimuli from one organ can lead to changes in another organ by integrated sensory pathways. In other words, stimulation of the bowel by certain dietary substances can modulate pelvic pain in interstitial cystitis/bladder pain syndrome (IC/BPS). [65]


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