What are the pathognomonic histologic findings characteristic of interstitial cystitis/bladder pain syndrome (IC/BPS)?

Updated: Dec 04, 2020
  • Author: Eric S Rovner, MD; Chief Editor: Edward David Kim, MD, FACS  more...
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Answer

No pathognomonic histologic findings exist for interstitial cystitis, although some authors have found increased numbers of mast cells in the detrusor muscle or submucosa in affected individuals. The finding of mast cells may suggest a potential role for antihistamine compounds in the treatment of the condition. However, this finding neither confirms nor excludes the diagnosis.


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