What is the diagnostic significance of a finding of glomerulations in the evaluation of interstitial cystitis/bladder pain syndrome (IC/BPS)?

Updated: Dec 04, 2020
  • Author: Eric S Rovner, MD; Chief Editor: Edward David Kim, MD, FACS  more...
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Answer

Glomerulations are not specific for interstitial cystitis, although some authors state that glomerulations are not present in healthy bladders. Others have speculated that the appearance of glomerulations may simply be a manifestation of chronic bladder underfilling due to hypersensitivity or sensory urgency rather than any specific primary pathologic process, such as interstitial cystitis. A systematic literature review by Wennevik et al found that glomerulations did not correlate with symptoms and were found in patients without IC/BPS. [55]


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