How are ulcers of bladder mucosa and areas with angiogenesis detected in the evaluation of interstitial cystitis/bladder pain syndrome (IC/BPS)?

Updated: Dec 04, 2020
  • Author: Eric S Rovner, MD; Chief Editor: Edward David Kim, MD, FACS  more...
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Answer

Researchers from the University of Pittsburgh reported that ulcers of bladder mucosa and areas with angiogenesis can be easily detected by using a flexible cystoscope with a narrow-band imaging (NBI) system. In their study of 52 patients, Ueda et al identified conventional ulcers in 37 patients, matching the accuracy of conventional cystoscopy. Moreover, in an additional 13 cases, NBI identified abnormal areas without ulcers, which were later correlated with areas of petechial hemorrhage and glomerulation after hydrodistension. The authors suggest that this system is highly practical for the diagnosis of interstitial cystitis/bladder pain syndrome (IC/BPS), but it has yet to be widely adopted. [54]


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